metolazone · Medicine question

What is the elimination half-life of metolazone?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Metolazone has a reported elimination half-life of 8–10 hours, with delayed excretion in people with impaired kidney function because its clearance is directly related to renal function.

Sources for this answer

Xaqua 5 mg TabletsRenascience Pharma Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 3Document updated 5 August 2025

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

What is the shelf life of Xaqua 5 mg metolazone tablets?Are any pharmaceutical incompatibilities listed for Xaqua 5 mg metolazone tablets?Can Xaqua 5 mg metolazone tablets be divided into equal halves?Can Xaqua metolazone increase blood sugar levels in people with diabetes?Does metolazone pass into breast milk in amounts that could harm a breastfed baby?How can metolazone affect the ability to drive or operate machinery?

loading page…

Answer

Sources for this answer

More questions about metolazone

Answer

Sources for this answer

More questions about metolazone

metolazone

More clinical questions?