Answer
The apparent plasma half-life of oxcarbazepine’s active metabolite MHD averages 9.3 ± 1.8 hours, increasing to 16–19 hours in patients with creatinine clearance below 30 mL/min following a single 300 mg Trileptal dose.
Sources for this answer
- Trileptal 150 mg, 300 mg, 600 mg Film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 32Document updated
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