Answer
Perampanel selectively and non-competitively antagonises ionotropic AMPA glutamate receptors on postsynaptic neurons, although the precise mechanism underlying its antiepileptic effects in humans remains incompletely understood.
Sources for this answer
- Perampanel Eisai 2mg film-coated tabletsEisai Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 24Document updated
Sources checked