Answer
Lacidipine has no human pregnancy safety data; animal studies found no teratogenicity but showed maternal toxicity at far-above-therapeutic doses and prolonged, difficult labour, so use requires maternal benefits to outweigh possible foetal or neonatal harm, considering uterine relaxation at term.
Sources for this answer
- Lacidipine 4 mg Film-Coated TabletsDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 6Document updated
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