Answer
Fosaprepitant and aprepitant’s fertility effects are not fully characterised because animal studies could not achieve exposures above human therapeutic levels, although those studies indicated no direct or indirect harmful effects on mating performance, fertility, embryonic/foetal development, or sperm count and motility.
Sources for this answer
- IVEMEND 150 mg powder for solution for infusionMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 16Document updated
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