brigatinib · Medicine question

What is known about brigatinib's effect on male fertility?

iatroX medicinesPublished 8 November 2026

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Answer

Brigatinib (Alunbrig) may reduce male fertility based on repeat-dose toxicity studies in male animals, but no human fertility data are available and the clinical relevance to human fertility is unknown.

Sources for this answer

Alunbrig 30 mg film-coated tabletsTakeda UK Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 11Document updated 29 July 2026

Sources checked 8 November 2026

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Can brigatinib be used during pregnancy?What is the recommendation on breastfeeding during brigatinib treatment?What does the Alunbrig (brigatinib) 30 mg film-coated tablet product information state about incompatibilities?Can brigatinib cause high blood pressure?Can brigatinib increase sensitivity to sunlight?Do Alunbrig (brigatinib) 30 mg film-coated tablets require any special storage conditions?

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