Citalopram · Medicine question

What is citalopram's mechanism of action as an antidepressant?

iatroX medicinesPublished 8 November 2026

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Citalopram is a potent, selective serotonin reuptake inhibitor (SSRI), inhibiting serotonin (5-HT) uptake with no or minimal effect on noradrenaline, dopamine or GABA uptake.

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Cipramil (Citalopram) 20 mg film-coated tabletsLundbeck Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 34Document updated 10 November 2023

Sources checked 8 November 2026

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