Answer
Concomitant use of capecitabine and phenytoin has been reported to increase phenytoin plasma concentrations, causing symptoms of phenytoin intoxication in individual cases; patients receiving both should have phenytoin plasma concentrations monitored regularly.
Sources for this answer
- Capecitabine Dr. Reddy's 500 mg Film-Coated TabletsDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 11Document updated
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