Answer
Combining vinorelbine with phenytoin is not recommended because vinorelbine may reduce phenytoin absorption and worsen convulsions, while phenytoin may increase vinorelbine's hepatic metabolism and reduce its efficacy.
Sources for this answer
- Navelbine 30mg soft capsulePierre Fabre Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 34Document updated
Sources checked