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Medicines pyrimethamineQuestion & answer

pyrimethamine · Medicine question

What interaction can occur between pyrimethamine and lorazepam?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Taking Daraprim (pyrimethamine) concurrently with lorazepam may induce hepatotoxicity (liver toxicity).

Sources for this answer

Daraprim TabletsGlaxoSmithKline UK · emc · SmPC §4.5 Interaction with other medicinal products · Version 23Document updated 2 January 2026

Sources checked 8 November 2026

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pyrimethamine

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