What interaction can occur between Minims Dexamethasone sodium phosphate eye drops and ritonavir or cobicistat?

With Minims Dexamethasone sodium phosphate eye drops, ritonavir or cobicistat may reduce dexamethasone clearance, increasing effects and causing adrenal suppression/Cushing’s syndrome; although unlikely clinically significant after ocular use, avoid combination unless benefits outweigh systemic corticosteroid risks, and monitor for systemic corticosteroid effects if combined.