Answer
Combining brimonidine tartrate + timolol eye drops with fluoxetine or paroxetine can potentiate systemic beta-blockade, with reported effects including decreased heart rate and depression.
Sources for this answer
- Brimonidine tartrate/Timolol 2mg/ml + 5mg/ml eye drops, solutionAspire Pharma Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
Sources checked