Answer
Avanafil and alpha-blockers can cause symptomatic hypotension in some patients through additive vasodilatory effects; patients should be stable on alpha-blocker therapy before starting Spedra (avanafil), initially at 50 mg.
Sources for this answer
- Spedra 50 mg tabletsA. Menarini Farmaceutica Internazionale SRL · emc · SmPC §4.4 Special warnings and precautions for use · Version 11Document updated
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