Answer
Adrenaline acid tartrate with propranolol may cause severe hypertension and reflex bradycardia through alpha-mediated vasoconstriction, while propranolol can antagonise adrenaline’s cardiac and bronchodilator effects, potentially preventing a response in severe anaphylaxis.
Sources for this answer
- Adrenaline (Epinephrine) Injection BP 1 in 1000hameln pharma ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 12Document updated
Sources checked