Answer
Activation of Abecma (idecabtagene vicleucel) by its target antigen, B-cell maturation antigen (BCMA), causes CAR-positive T-cell proliferation, cytokine secretion and subsequent cytolytic killing of BCMA-expressing cells.
Sources for this answer
- Abecma 260 - 500 x 10^6 cells dispersion for infusionBristol Myers Squibb Pharmaceuticals limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated
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