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Medicines methoxsalenQuestion & answer

methoxsalen · Medicine question

What happens to DNA when methoxsalen is activated by UVA light?

iatroX medicinesPublished 8 November 2026

The answer

Answer

When activated by UVA light, methoxsalen binds to pyrimidine bases and forms covalent cross-links between the two DNA strands.

Sources for this answer

UVADEX 20 micrograms/ml Solution for Blood Fraction ModificationTherakos (UK) Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 3Document updated 16 July 2025

Sources checked 8 November 2026

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methoxsalen

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