riluzole · Medicine question

What effects on fertility were observed in rats given riluzole at doses above the therapeutic dose?

Name: What effects on fertility were observed in rats given riluzole at doses above the therapeutic dose?
Published: 2026-11-08T14:33:12.836Z

iatroX medicinesPublished 8 November 2026

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Riluzole at 15 mg/kg/day, above the therapeutic dose, caused slight impairment of reproductive performance and fertility in rats, probably due to sedation and lethargy.

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Riluzole 50 mg film-coated tabletsRanbaxy (UK) Limited a Sun Pharmaceutical Company · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 8Document updated 14 May 2026

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