Answer
Mecasermin had no effects on fertility in rats given intravenous doses of 0.25, 1 and 4 mg/day, representing up to four times the clinical exposure at the maximum recommended human dose based on AUC.
Sources for this answer
- Increlex 10 mg/ml solution for injectionEsteve Pharmaceuticals (formerly Intrapharm Laboratories) · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 2Document updated
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