Answer
Efavirenz did not impair mating or fertility in male or female rats at doses up to 100 mg/kg twice daily, with fertility evaluated only at systemic exposures equivalent to or below those in humans receiving recommended doses.
Sources for this answer
- Efavirenz 600 mg film-coated tabletsAurobindo Pharma - Milpharm Ltd. · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 12Document updated
Sources checked