digoxin · Medicine question

What ECG changes can digoxin cause at therapeutic doses?

iatroX medicinesPublished 8 November 2026

The answer

Answer

At therapeutic doses, digoxin may prolong the PR interval and depress the ST segment, and may produce false-positive ST-T changes during exercise testing; these are expected drug effects, not indications of toxicity.

Sources for this answer

Digoxin 125 micrograms tabletsAspen · emc · SmPC §4.4 Special warnings and precautions for use · Version 26Document updated 21 May 2026

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

Do digoxin 125 micrograms tablets in the Aspen product contain lactose?How can digoxin affect the heart rhythm in people with sick sinus syndrome?Does digoxin pass into breast milk, and is breastfeeding contraindicated?How can amiodarone affect digoxin when taken together?How can St John's wort affect digoxin?Is digoxin contraindicated during pregnancy?

loading page…

Answer

Sources for this answer

More questions about digoxin

Answer

Sources for this answer

More questions about digoxin

digoxin

More clinical questions?