What does the Progynova (estradiol valerate) product information report about teratogenic or foetotoxic effects following inadvertent foetal exposure to oestrogens?

Progynova (estradiol valerate) product information reports that most relevant epidemiological studies to date indicate no teratogenic or foetotoxic effects following inadvertent foetal exposure to oestrogens, but Progynova is not indicated during pregnancy and treatment should be withdrawn immediately if pregnancy occurs.