Answer
Bendamustine should not be used during pregnancy unless clearly necessary because human data are insufficient and nonclinical studies showed embryo-/fetolethality, teratogenicity and genotoxicity; if treatment is absolutely necessary or pregnancy occurs during treatment, inform the patient of fetal risks, monitor carefully and consider genetic counselling.
Sources for this answer
- Bendamustine hydrochloride 180 mg/4 ml Concentrate For Solution For InfusionDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 8Document updated
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