Answer
Cardiac failure has been reported when pioglitazone is combined with insulin such as Levemir (insulin detemir), especially in patients with risk factors for heart failure.
Sources for this answer
- Levemir Penfill 100 units/ml solution for injection in cartridge.Novo Nordisk Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 1Document updated
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