Answer
Serious multiple congenital abnormalities have been reported after cyclophosphamide use during the first trimester, although pregnancy data are very limited and the passage does not name specific defects.
Sources for this answer
- Cyclophosphamide 2000 mg Powder for Solution for Injection or InfusionSandoz Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 5Document updated
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