What are the signs of neuroleptic malignant syndrome associated with olanzapine?

Signs of olanzapine-associated neuroleptic malignant syndrome include very high fever, muscle rigidity, altered mental status and autonomic instability (irregular pulse or blood pressure, fast heartbeat, sweating and cardiac dysrhythmia), with possible elevated creatine phosphokinase, myoglobinuria (rhabdomyolysis) and acute renal failure.