Answer
Combining eszopiclone with opioids increases the risk of sedation, respiratory depression, coma and death through additive central nervous system depression, so the dosage and duration of combined use should be limited.
Sources for this answer
- Lunivia 1 mg film-coated tabletsaxunio Pharma GmbH · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated
Sources checked