What are the plasma half-lives of piperacillin and tazobactam in healthy subjects receiving piperacillin/tazobactam?

Following single or multiple doses of piperacillin/tazobactam in healthy subjects, the plasma half-lives of both piperacillin and tazobactam range from 0.7 to 1.2 hours, unaffected by dose or infusion duration.