brimonidine tartrate + timolol · Medicine question

What are the approximate systemic half-lives of the two active ingredients in brimonidine tartrate + timolol eye drops?

Name: What are the approximate systemic half-lives of the two active ingredients in brimonidine tartrate + timolol eye drops?
Published: 2026-11-08T13:41:11.281Z

iatroX medicinesPublished 8 November 2026

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For brimonidine tartrate + timolol eye drops, brimonidine’s mean apparent systemic half-life after topical dosing is approximately 3 hours, while timolol’s plasma half-life is about 7 hours.

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Brimonidine tartrate/Timolol 2mg/ml + 5mg/ml eye drops, solutionAspire Pharma Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 1Document updated 6 November 2025

Sources checked 8 November 2026

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