Answer
Lithium combined with high doses of chlorpromazine hydrochloride can cause confusional syndrome, hypertonia and hyper-reflexivity, occasionally with rapidly increased serum lithium concentrations, and rare cases of neurotoxicity have been reported.
Sources for this answer
- Chlorpromazine Hydrochloride 100mg/5ml Oral SyrupRosemont Pharmaceuticals Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 11Document updated
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