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Medicines denosumabQuestion & answer

denosumab · Medicine question

Should Prolia (denosumab) 60 mg pre-filled syringes be shaken before use?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Prolia (denosumab) 60 mg pre-filled syringes must not be shaken before use.

Sources for this answer

Prolia 60 mg solution for injection in pre-filled syringeAmgen Ltd · emc · SmPC §6.6 Special precautions for disposal and other handling · Version 38Document updated 23 July 2026

Sources checked 8 November 2026

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More questions about denosumab

How many pre-filled syringes are in a Prolia (denosumab) 60 mg pack, and what volume does each contain?How should Prolia (denosumab) 60 mg pre-filled syringes be stored and protected from light?What is the shelf life of Prolia (denosumab) 60 mg pre-filled syringes when stored as recommended?What does Prolia (denosumab) 60 mg solution for injection in a pre-filled syringe look like?Can Prolia (denosumab) 60 mg solution for injection be mixed with other medicinal products?

denosumab

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