Answer
Usually not. In pre-filled syringes the bubble is intentional; follow the instructions for the supplied product.
Sources for this answer
- Inhixa 4,000 IU (40 mg)/0.4 mL solution for injection — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.