Answer
Yes. It can increase anaesthetic-related hypotension and mask the usual heart-rate response to sudden blood loss.
Sources for this answer
- Labetalol 400 mg Film-coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
- Labetalol 5 mg/ml solution for injection/ infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.