Cause and triggers
Scalp psoriasis is a manifestation of psoriasis, a systemic immune-mediated inflammatory skin disease with a chronic relapsing–remitting course. NICE CKS
The context identifies factors associated with psoriasis onset or exacerbation rather than a single cause: infection, medicines including corticosteroid withdrawal, ultraviolet-light exposure, skin trauma, hormonal change, stress, smoking, and alcohol. NICE CKS
It is not an infectious condition. NICE CKS
Evidence-based management in adults
- Give information that treatment aims to control symptoms rather than cure psoriasis, and that complete clearance may not be possible. NICE CKS
- Address potentially modifiable exacerbating factors with smoking cessation, alcohol intake within recommended limits, weight loss where appropriate, and assessment and management of stress, distress, anxiety, or depression. NICE CKS
- Use a scalp-appropriate vehicle, such as a lotion, solution, or gel, taking account of preferences, cosmetic acceptability, and practical application. NICE CKS
- First line: offer a potent topical corticosteroid once daily for up to 4 weeks, with instruction on safe application. NICE CG153
- Review after 4 weeks; if there is a good response, continue until clear or nearly clear, but do not use a potent corticosteroid for more than 8 weeks at any one site and use a 4-week treatment break before restarting. NICE CKS
- If response is inadequate at 4 weeks, check adherence and acceptability, consider another potent-steroid formulation such as shampoo or mousse, and/or remove adherent scale with salicylic-acid preparations, emollients, or oils before applying the corticosteroid. NICE CG153
- If control remains unsatisfactory after a further 4 weeks, offer once-daily calcipotriol/betamethasone dipropionate combination treatment for up to 4 weeks; alternatively, use once-daily vitamin D or vitamin D analogue only when corticosteroids cannot be used and disease is mild to moderate. NICE CG153
- Coal-tar shampoo is an option, but should not be used alone in severe scalp psoriasis because it is less effective than other scalp treatments and unlikely to be clinically or cost effective as sole therapy. NICE CKS
- Consider dermatology referral when lesions are extensive, severe, or do not respond to topical treatment; topical treatment alone may be insufficient for extensive disease or psoriasis graded moderate or worse. NICE CKS
- For plaque psoriasis not controlled with topical treatment alone, narrowband UVB phototherapy is recommended; systemic treatments and targeted immunomodulatory treatments are specialist options for more extensive or refractory disease. NICE CG153
In a trial of 312 people with at least moderate scalp psoriasis, once-daily calcipotriol/betamethasone gel achieved absent or very mild disease at week 8 in 68.6% of participants, versus 31.4% with calcipotriol scalp solution twice daily. SmPC Calcipotriol/Beta