Perianal fistulas are surgically classified primarily based on their anatomical relation to the anal sphincter complex, following the Parks classification, which is widely accepted in clinical practice and supported by imaging modalities such as MRI and ultrasound for detailed assessment.
The main types of perianal fistulas include:
- Intersphincteric fistulas: These are the most common type (50-80% of cryptoglandular fistulas), where the fistula tract runs between the internal and external anal sphincters, passing through the internal sphincter and opening externally on the skin without crossing the external sphincter. They can be effectively treated by fistulotomy with minimal risk to continence Jimenez and Mandava N. 2026 Jimenez & Mandava N 2026 Hosokawa T. 2026 Hosokawa T 2026.
- Transsphincteric fistulas: The tract crosses both the internal and external sphincters, extending through the external sphincter before exiting near the perianal skin. These require more complex management due to sphincter involvement, often involving staged procedures or seton placement to preserve continence Jimenez and Mandava N. 2026 Jimenez & Mandava N 2026 Hosokawa T. 2026 Hosokawa T 2026.
- Suprasphincteric fistulas: These fistulas track above the external sphincter, passing superiorly over the puborectalis muscle before descending to the external opening. They bypass the external sphincter but involve the internal sphincter and puborectalis muscle. Management may involve seton placement prior to fistulotomy Jimenez and Mandava N. 2026 Jimenez & Mandava N 2026 Hosokawa T. 2026 Hosokawa T 2026.
- Extrasphincteric fistulas: These lesions typically arise from the rectum or proximal anal canal and track outside both sphincters, often as sequelae of trauma or surgical procedures. They show external openings in the perianal region but the tract ascends to the rectal lumen above the dentate line. Due to their complexity and atypical anatomy, further evaluation and tailored management are necessary Jimenez and Mandava N. 2026 Jimenez & Mandava N 2026 Hosokawa T. 2026 Hosokawa T 2026.
In addition to the Parks classification, the St. James University Hospital (SJUH) MRI-based grading system refines the surgical classification by grading fistulas from Grade 1 to Grade 5, incorporating the presence of abscesses and secondary tracts, and tracts crossing sphincters or extending above the levator ani muscle. This imaging classification aids in preoperative planning and prognosis prediction Jimenez and Mandava N. 2026 Jimenez & Mandava N 2026 PubMed Sharma et al. 2016 PubMed O'Malley et al. 2012.
Awareness of these types is crucial for clinical decision-making, as the extent of sphincter involvement influences the choice of surgical technique to balance disease eradication and continence preservation. Low fistulas (intersphincteric and low transsphincteric) typically allow simpler treatment such as fistulotomy, whereas high or complex fistulas (suprasphincteric, extrasphincteric, and complex transsphincteric) often require sphincter-sparing approaches like seton placement, ligation of the intersphincteric fistula tract (LIFT), or advancement flap repair Jimenez and Mandava N. 2026 Jimenez & Mandava N 2026 Gujar et al. 2026 Gujar et al. 2026.
Key References
- NICE CKS: Anal fissure
- NICE CKS: Pilonidal sinus disease
- NICE NG125: Surgical site infections: prevention and treatment
- NICE CG49: Faecal incontinence in adults: management
- (Schouten et al., 2001): [Gastrointestinal surgery and gastroenterology. XIII. Classification and diagnosis of perianal fistulas].
- (O'Malley et al., 2012): Rectal imaging: part 2, Perianal fistula evaluation on pelvic MRI--what the radiologist needs to know.
- (Sharma et al., 2016): Magnetic resonance imaging in perianal fistulas-A pictorial atlas.
- (Jimenez and Mandava N., 2026): Anorectal Fistula
- (Hosokawa T., 2026): Perianal Sonographic Approach to Fistula-in-Ano and Perianal Abscesses: A Pictorial Review.
- (Gujar et al., 2026): Clinical Patterns and Treatment Outcomes of Selected Benign Anorectal Conditions in a Tertiary Care Hospital in Vijayapura, India: A Retrospective Observational Study.