When should I consider referring a patient with recurrent Mycoplasma genitalium infections to a specialist?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Consider referring a patient with recurrent Mycoplasma genitalium infections to specialist sexual health services when:

  • They have difficulty with partner notification or require support in managing partner notification, as specialist services have expertise in contact tracing and counselling for STIs.
  • There is a need for seamless referral pathways to ensure appropriate management and partner notification without requiring self-referral.
  • The infection is recurrent despite initial treatment, indicating possible antibiotic resistance or complex management needs that require specialist input.

Specialist sexual health services can provide comprehensive assessment, tailored treatment, and support for partner notification to reduce reinfection risk and transmission.

These recommendations align with NICE guidance emphasizing the importance of referral to specialist services for complex STI cases and partner notification support .

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