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How should I manage a patient diagnosed with HELLP syndrome in a primary care setting before referral to secondary care?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 22 August 2025

Management of a patient diagnosed with HELLP syndrome in primary care before referral:

  • Urgent referral to secondary care: HELLP syndrome is a severe complication of pre-eclampsia characterised by haemolysis, elevated liver enzymes, and low platelet count, requiring immediate hospital admission for specialist management. Refer the patient urgently to secondary care without delay 1.
  • Initial assessment and monitoring: In primary care, perform a full clinical assessment including blood pressure measurement and review of symptoms such as right upper quadrant or epigastric pain, severe headache, visual disturbances, or signs of bleeding 1.
  • Do not delay transfer: Do not attempt to manage HELLP syndrome definitively in primary care; stabilise the patient as much as possible and arrange rapid transfer to hospital for monitoring and treatment 1.
  • Blood pressure control: If severe hypertension (≥160/110 mmHg) is present, and if trained and authorised, consider initial antihypertensive treatment (e.g., labetalol) to reduce risk of complications while awaiting transfer, but do not delay referral 1.
  • Avoid invasive procedures: Avoid any invasive procedures or treatments that require specialist supervision in primary care.

Summary: The priority in primary care is urgent recognition, initial assessment, and immediate referral to secondary care for a patient with HELLP syndrome, as this condition requires specialist inpatient management 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.