What are the recommended follow-up protocols for monitoring renal function and pulmonary symptoms in patients treated for Goodpasture's syndrome?

Recommended follow-up protocols for monitoring renal function and pulmonary symptoms in patients treated for Goodpasture's syndrome include:

• Renal function monitoring: Regular assessment of renal function through blood tests (e.g., serum creatinine, eGFR) and urinalysis to detect ongoing or worsening kidney involvement is essential, although specific intervals are not detailed in the provided guidelines.
• Pulmonary symptom monitoring: Follow-up should include assessment of lung function and symptoms to monitor pulmonary involvement and progression.
• For pulmonary follow-up, consider scheduling appointments every 3 to 6 months depending on disease stability and progression, with more frequent reviews if rapid deterioration occurs.
• Assess for oxygen therapy needs, pulmonary rehabilitation, and identify exacerbations or hospital admissions related to respiratory symptoms.
• Consider referral to specialist services such as interstitial lung disease specialists or lung transplantation assessment if indicated.
• Address comorbidities and psychosocial needs, and consider palliative care referral as appropriate.

These recommendations align with protocols for interstitial lung diseases with pulmonary involvement, such as idiopathic pulmonary fibrosis, which share some clinical monitoring principles with Goodpasture's syndrome pulmonary manifestations ¹.