What are the recommended referral pathways for a patient with suspected Ewing sarcoma in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

For suspected Ewing sarcoma in primary care, consider a very urgent referral (for an appointment within 48 hours) if an X-ray suggests the possibility of bone sarcoma, which includes Ewing sarcoma .

Specifically, if an X-ray indicates the possibility of bone sarcoma, a very urgent referral should be made for specialist assessment .

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