Which investigations should be considered in a patient presenting with new-onset dystonia?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 22 August 2025Updated: 22 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Investigations for new-onset dystonia:

  • In adults presenting with suspected dystonia, routine cervical imaging is not recommended to evaluate the condition.
  • Referral for neurological assessment is advised to confirm diagnosis and consider treatment options such as botulinum toxin therapy.
  • Consider medication history carefully, as antipsychotic and antiemetic drugs can trigger or worsen dystonia.
  • In children with sudden-onset dystonia, urgent neurological assessment is recommended.

Overall, the initial approach focuses on clinical assessment and specialist referral rather than routine imaging or laboratory investigations in primary care.

Summary: No routine imaging or specific laboratory tests are recommended initially; instead, refer for specialist neurological assessment to establish diagnosis and management.

References:

Educational content only. Always verify information and use clinical judgement.