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Which laboratory tests are essential for confirming a diagnosis of CVID in a patient with recurrent infections?
Answer
The provided UK guidelines and PubMed literature do not specify the essential laboratory tests for confirming a diagnosis of common variable immunodeficiency (CVID) in a patient presenting with recurrent infections.
The available PubMed literature discusses aspects of common variable immunodeficiency such as cutaneous granulomas [ (Aghamohammadi et al., 2010) ] and an approach to CVID in horses [ (Mullen and Felippe, 2024) ], but does not detail human diagnostic criteria or specific laboratory tests.
The UK guidelines provided cover coeliac disease 1, vitamin B12 deficiency 2, and bacterial meningitis 3, which are not directly related to the diagnostic laboratory tests for CVID.
Key References
- NG20 - Coeliac disease: recognition, assessment and management
- NG239 - Vitamin B12 deficiency in over 16s: diagnosis and management
- NG240 - Meningitis (bacterial) and meningococcal disease: recognition, diagnosis and management
- (Aghamohammadi et al., 2010): Cutaneous granulomas in common variable immunodeficiency: case report and review of literature.
- (Mullen and Felippe, 2024): The Horse with Recurrent Fevers and Infections: Approach to Common Variable Immunodeficiency.
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