Referral to a toxicology specialist, typically via the National Poisons Information Service (NPIS), is indicated for severe or complex cases of suspected overdose NICE CKS. This includes situations involving multiple ingestions NICE CKS.
Additionally, referral is advised for people with significant comorbidities NICE CKS. Cases where the specific poison is unknown also warrant consultation with the NPIS NICE CKS. The NPIS provides information and advice to NHS staff to assist in deciding whether a person needs admission or can be managed at home, and offers advice on hospital management for those requiring admission NICE CKS. The service is available 24 hours a day and is supported by a team of on-call consultant clinical toxicologists NICE CKS.