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What investigations are recommended for a patient with recurrent syncope and no clear diagnosis after initial assessment?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
For patients with recurrent syncope and no clear diagnosis after initial assessment, the recommended investigations include a specialist cardiovascular assessment, which involves a detailed history, physical examination, and repeat 12-lead ECG, as well as examination of previous ECG recordings 1.
If structural heart disease is suspected, appropriate investigations such as cardiac imaging should be undertaken 1.
Further testing may include investigations for suspected cardiac arrhythmic causes, postural hypotension, or neurally mediated syncope, as directed by the specialist assessment 1.
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