What are the contraindications for yellow fever vaccination in adults?

Contraindications for yellow fever vaccination in adult patients include:

• History of thymus disease or thymectomy, as these patients have a higher risk of yellow fever vaccine-associated viscerotropic disease (YEL-AVD), which can be fatal ¹,².
• Age 60 years or older, due to increased risk of neurological and viscerotropic adverse events following vaccination ¹,².
• Known severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine or previous dose of yellow fever vaccine ¹,².
• Immunocompromised individuals or those with certain immune deficiencies, as the vaccine is live-attenuated and may cause serious adverse effects (implied from expert opinion in The Green Book) ¹,².

Patients who cannot receive the vaccine and are travelling to countries requiring proof of vaccination should request a letter of exemption from a Yellow Fever Vaccination Centre or their treating practitioner ¹,².