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What are the key clinical features that suggest a diagnosis of interstitial lung disease in a primary care setting?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Key clinical features suggesting interstitial lung disease (ILD) in primary care include:

  • Age over 45 years
  • Persistent breathlessness on exertion
  • Persistent cough
  • Bilateral inspiratory crackles on chest auscultation
  • Clubbing of the fingers
  • Spirometry findings that are normal or show a restrictive pattern, though sometimes an obstructive pattern may be present

These features should prompt consideration of ILD and may warrant chest X-ray and referral to a specialist for further assessment and diagnosis 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.