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What are the recommended first-line topical treatments for a child diagnosed with impetigo?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Recommended first-line topical treatments for a child diagnosed with impetigo:

  • For localized non-bullous impetigo in children who are not systemically unwell or at high risk of complications, hydrogen peroxide 1% cream applied two to three times daily for 5 days is recommended as the first-line treatment.
  • If hydrogen peroxide 1% cream is unsuitable (for example, if the impetigo is around the eyes), topical fusidic acid 2% cream applied three times daily for 5 days should be offered.
  • If fusidic acid resistance is suspected or confirmed, topical mupirocin 2% cream applied three times daily for 5 days is recommended as an alternative.

Reassessment is advised if symptoms worsen rapidly or do not improve after completing the treatment course.

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This content was generated by iatroX. Always verify information and use clinical judgment.