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What are the contraindications for prescribing HRT that I should be aware of in my practice?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Contraindications for prescribing hormone replacement therapy (HRT) include a personal history of breast cancer or high risk of breast cancer, where HRT should not be routinely offered and referral to a specialist is recommended 2.

HRT should be stopped in women diagnosed with breast cancer, in line with NICE guidelines 2.

HRT is contraindicated in individuals with hormone-sensitive cancers or conditions where hormones may exacerbate the condition, and advice should be sought from a healthcare professional with expertise in the condition 2.

Women with contraindications to hormonal treatments should be advised accordingly, including those with certain medical conditions that may be affected by HRT 2.

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This content was generated by iatroX. Always verify information and use clinical judgment.