What investigations are indicated for a patient with unilateral hearing loss?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

For a patient presenting with unilateral hearing loss, an audiological assessment should be arranged, including pure tone audiometry to differentiate conductive from sensorineural hearing loss and to characterize the severity and pattern of hearing loss at various frequencies .

Consider referral for additional diagnostic assessment if there are specific symptoms such as sudden or rapid onset of hearing loss, or if the hearing loss is unexplained by external or middle ear causes .

Offer MRI of the internal auditory meati to adults with hearing loss and localising symptoms or signs (such as facial nerve weakness) that might indicate a vestibular schwannoma or CPA lesion, irrespective of pure tone thresholds .

Consider MRI of the internal auditory meati for adults with sensorineural hearing loss and no localising signs if there is an asymmetry on pure tone audiometry of 15 dB or more at any 2 adjacent test frequencies, using test frequencies of 0.5, 1, 2, 4 and 8 kHz .

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