How should I approach the management of dermatomyositis in a patient with associated malignancy?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 16 August 2025Updated: 16 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The management of dermatomyositis in a patient with an associated malignancy requires a dual approach, focusing on both the myositis and the underlying cancer . A crucial aspect of this management is the identification and treatment of the associated malignancy, as addressing the cancer can often lead to an improvement in the dermatomyositis symptoms . Therefore, general principles for the recognition and referral of suspected cancer should be followed to ensure timely diagnosis of the underlying malignancy . If metastatic malignant disease is present, its management should adhere to established guidelines . Alongside cancer treatment, immunosuppressive therapies are typically employed to manage the symptoms of dermatomyositis itself .

Educational content only. Always verify information and use clinical judgement.