What are the recommended management strategies for a patient diagnosed with AKI, particularly regarding fluid management and medication adjustments?

Fluid management in acute kidney injury: Monitor serum creatinine regularly and assess clinical need to guide fluid management, with daily measurement typical in hospital settings ¹.

Consider cautious fluid resuscitation to maintain adequate perfusion, but avoid fluid overload, which can worsen pulmonary oedema and other complications ¹.

Medication adjustments: Reconsider the use of potentially nephrotoxic drugs, including NSAIDs, aminoglycosides, ACE inhibitors, ARBs, and diuretics, and consider temporarily stopping these medications until renal function stabilizes ¹, ³.

Seek advice from a pharmacist about optimizing medicines and drug dosing in patients with or at risk of AKI ³.