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What are the key clinical features that should raise suspicion for Acute Lymphoblastic Leukaemia (ALL) in a child?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Key clinical features that should raise suspicion for acute lymphoblastic leukaemia in a child include:

  • General symptoms: Persistent fatigue, unexplained fever, and unexplained and persistent infections 1.
  • Haematological signs: Unexplained petechiae, unexplained bleeding or bruising, and pallor 1.
  • Lymphatic and organ enlargement: Generalised lymphadenopathy and unexplained hepatosplenomegaly 1.
  • Skeletal symptoms: Persistent or unexplained bone pain 1.

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This content was generated by iatroX. Always verify information and use clinical judgment.